Replicative Capacity of MERS Coronavirus in Livestock Cell Lines
Identifieur interne : 001B01 ( Main/Exploration ); précédent : 001B00; suivant : 001B02Replicative Capacity of MERS Coronavirus in Livestock Cell Lines
Auteurs : Isabella Eckerle ; Victor M. Corman ; Marcel A. Müller ; Matthias Lenk ; Rainer G. Ulrich ; Christian DrostenSource :
- Emerging Infectious Diseases [ 1080-6040 ] ; 2014.
Descripteurs français
- KwdFr :
- MESH :
- génétique : ARN viral.
- physiologie : Coronavirus, Réplication virale.
- virologie : Capra, Chameaux.
- Animaux, Interactions hôte-pathogène, Lignée cellulaire, Moyen Orient, Spécificité d'hôte.
English descriptors
- KwdEn :
- MESH :
- chemical , genetics : RNA, Viral.
- physiology : Coronavirus, Virus Replication.
- virology : Camelus, Goats.
- Animals, Cell Line, Host Specificity, Host-Pathogen Interactions, Middle East.
Abstract
Replicative capacity of Middle East respiratory syndrome coronavirus (MERS-CoV) was assessed in cell lines derived from livestock and peridomestic small mammals on the Arabian Peninsula. Only cell lines originating from goats and camels showed efficient replication of MERS-CoV. These results provide direction in the search for the intermediate host of MERS-CoV.
Url:
DOI: 10.3201/eid2002.131182
PubMed: 24457147
PubMed Central: 3901466
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>Replicative capacity of Middle East respiratory syndrome coronavirus (MERS-CoV) was assessed in cell lines derived from livestock and peridomestic small mammals on the Arabian Peninsula. Only cell lines originating from goats and camels showed efficient replication of MERS-CoV. These results provide direction in the search for the intermediate host of MERS-CoV.</p>
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